Basal ganglia calcification in Down's syndrome.

Basal ganglia calcification and psychosis in Down's syndrome.

A case of basal ganglia calcification (diagnosed in vivo) and schizophreniform psychosis occurring in a young adult with Down's syndrome is reported. A stress-vulnerability model is suggested. Because of the relatively high prevalence of basal ganglia calcification to Down's syndrome, this population appears well suited for systematic study of the neuropsychiatric aspects associated with this n...

A man with purple toes.

1 Wisniewski KE, French JH, Rosen JF, Koslowski PB, Tenner M, Wisniewski HM. Basal ganglia calcification (BGC) in Down's syndrome. Another manifestation of premature aging. Ann NYAcad Sci 1982;396:179-89. 2 Jakab I. Basal ganglia calcification and psychosis in mongolism. Eur Neurol 1978;17:300-14. 3 Lowenthal A, De Deyn P. Striopallidodentate calcifications. In: Joseph AB, Young RR, eds. Moveme...

Fahr disease: Idiopathic basal ganglia calcification

Intracranial calcification in a patient with HDR syndrome and a GATA3 mutation.

Hypoparathyroidism, sensorineural deafness and renal dysplasia (HDR) syndrome is an autosomal dominant disorder (1). We herein demonstrate the brain computed tomography (CT) findings of a 31-year-old woman with HDR syndrome caused by a GATA3 heterozygous mutation (2). Her 1-year-old son had renal cystic dysplasia. Brain CT revealed bilateral and symmetrical calcifications in the basal ganglia, ...

Congenital Rubella Syndrome with Basal ganglia calcification and Bilateral Nuclear Cataracts in a Neonate: A Rare Entity

In-utero transmission of rubella virus during pregnancy leads to congenital Rubella syndrome (CRS), which is characterized by cataracts, deafness and sensorineural hearing loss. While the nuclear cataract is the most frequently occurring abnormality, basal ganglia calcification is a rarer manifestation. The Risk of fetal transmission of rubella virus is highest during the first 12 weeks of gest...